the benzyl alcohol in question, 2-amino-5-bromobenzyl alcohol, is obtained from the corresponding benzoic acid via lithium aluminium hydride reduction in tetrahydrofuran. bleah! LAH isn't fun stuff. reacts explosively with water, and in fact the moisture from air is capable of setting the stuff on fire
but the TEMPO oxidation is straightforward. other oxidizing reagents might be expected to attack the aniline ring (aminobenzenes or anilines are notoriously sensitive to oxidation)
oh I haven't done _Organic Syntheses_ roulette.
hm, nothing matches 7667
but 5727 matched two articles! here's the first one
http://orgsyn.org/demo.aspx?prep=v90p0240
while back I talked a bit about a class of reagents based on a substance nicknamed "TEMPO", or 2,2,6,6-tetramethylpiperidinyl-1-oxyl radical, a stable nitroxyl radical compound that is the basis for a family of oxidation reactions in organic synthesis
this is one such reaction, using TEMPO in an oxidation of a benzyl alcohol to a benzaldehyde
@packbat gnite!
Parallax webcomic, p. 33 (argh argh argh)
bleh, anyway
central figure is the new improved Lomax, in anime garb, the lozenge sending rays of light out in the form of an X, dividing up the page
to their left, Prof. Rodgers with the wooden box
to their right, two figures...parents perhaps? the better-seen figure definitely looks like mom. (we've got a weird memory when it comes to faces cos of the aphantasia thing)
Parallax webcomic, p. 33 (argh argh argh)
ok, we're at a title card, basically
https://www.parallaxcomic.com/comic/end-of-chapter-one
"end of chapter one" although the subtitle says "0: Up Is The Only Way" so maybe that was really chapter zero? haha
a signature says "M. Falke". got no idea who that is even though I've met at least a couple of the people who've worked on this
we've all had like, twenty names apiece at least
all of us in involved in this goddamn tire fire
Parallax webcomic, p. 31
page thirty-two
https://www.parallaxcomic.com/comic/page-32
Lomax hides in the bathroom again, squatting with both butt and feet on the toilet bowl lid (you know I don't think any of us has ever done that, sat on the toilet completely off the ground, but I won't swear to it)
Lomax looks like utter hell
they dial the number (which I DID dial myself btw, although I was pretty sure it was invalid, and it was)
"Mr. Rogers?" (again it's wrong) "I need help"
@troubleMoney something that filtered into here from twitter, it's ridiculous
Parallax webcomic, p. 31
flashback time: Lomax remembers Prof. Rodgers holding out the little wooden box and saying, "if you really want to change, this might be useful. you can talk to me."
hm
"Mr. Rogers!" says Lomax. ("Rogers", note, not "Rodgers". another slip?) unsteadily the kid fumbles for the slip of paper with a phone number
Parallax webcomic, p. 31
okay, we're feeling a bit better now
page thirty-one
https://www.parallaxcomic.com/comic/page-31
nice page layout here, with a horizontal strip in the middle used to illustrate a flashback
Lomax is at wit's end. they try to pull off the strange new outfit and it won't come off (I always wonder about that stuff, with tokusatsu outfits...like, do the clothes even come off?)
in the bathroom mirror they look at the glowing pink lozenge now in their forehead, baffled
Parallax webcomic, p. 29, family drama
Lomax's mom hollers out the question, "are you all right?" Lomax is not all right, and their bafflement is extreme
so is their cat's. Ramsay hisses in fright in a corner, then dashes out of the room in one bound
(btw, after Kara / Chara had somehow achieved soulbonding with all three of the Toriel kids, and was trying to relax on the couch, our cat Gibbs came up and regarded Chara from a short distance away. definitely questioning. no hissing tho)
Parallax webcomic, p. 29, family drama
perfection is spoiled again. page twenty-nine
https://www.parallaxcomic.com/comic/page-29
Lomax screams loud enough to be heard outside, startling a passing bird. curiously the window to his room has _two_ horizontal cross bars, not one, as seen from inside. maybe a blunder
🔴 or a different window
Lomax's collision with default reality is a rough one. apparently they collided with the floor, too; Lomax vaguely remembers floating in the air
sesame street, autism advocacy, anti-autism, medicalization (---)
@packbat RAEG
Chara's already out for blood on this one
sesame street, autism advocacy, anti-autism, medicalization (---)
Sesame Street has given up working with ASAN to work with Autism Speaks instead. https://autisticadvocacy.org/2019/08/asan-has-ended-partnership-with-sesame-street/
Excerpt from the linked open letter:
====
For several years, ASAN consulted with Sesame Street on their See Amazing project and the development of their autistic character, Julia. Until this summer, the content Sesame Street produced showed parents that their autistic children could live great lives, and taught autistic and neurotypical children ways to become friends. Through this approach, See Amazing successfully encouraged the inclusion of autistic children in their communities, and had a widespread positive impact.
Sesame Street has now decided to undo that progress. Its latest PSAs featuring Julia promote Autism Speaks’ “Screen for Autism” initiative and their resource for parents of newly-diagnosed autistic children, the 100 Day Kit. Like much of Autism Speaks’ recent advertising, these PSAs use the language of acceptance and understanding to push resources that further stigma and treat autistic people as burdens on our families. The 100 Day Kit encourages parents to blame family difficulties on their autistic child (“When you find yourself arguing with your spouse… be careful not to get mad at each other when it really is the autism that has you so upset and angry”) and to view autism as a terrible disease from which their child can “get better.” It recommends compliance-based “therapies” and pseudoscientific “autism diets,” but fails to educate families about communication supports. It even instructs parents to go through the five stages of grief after learning that their child is autistic, as they would if the child had died.
====
so nobody (of course) answered my question about what happened to witchcraft.cafe
well, what happened to witchcraft.cafe?
PLEASE?