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1/2 “Beautifully surprising” to whom, exactly? How many studies and experiments do we need before we can just make this standard policy??

If I were homeless and couldn’t afford to eat regularly, and if some kind stranger gave me a few dollars, that wouldn’t be nearly enough to change my circumstances. So yeah, I might spend it on some drugs to help me feel some temporary relief from hunger pangs and the constant beatdown of life in this harsh society. But if I received enough money to get a room that isn’t infested with vermin and enough to know I could eat for the next month? THAT might help me get on my feet.

Desperate people do desperate things. Less desperate people do fewer desperate things. It’s so simple.

cbc.ca/news/canada/british-col

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(Boost if this makes you angry too.)

❄ fans of media get so bogged down in who is or is not “canonically” trans I just solve this once and for all by making everyone trans and nothing canon

@bodger but is it really a bot or is it a call center in India that they like to pretend are bots so their end users don't notice that it's underpaid human labor?

Taking walks at the lake with the Gameboy Camera is becoming a more regular thing.

It's nice to have something small but not innately serious, like my Fuji GFX, to carry around, and the results are super fun!

I haven't been feeling up to hiking for mushroom photos lately though, and I really would like to get back out before fall hits!
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#lazyhobbies #photography #digitalart #pixelart #birding #birdphotography #gameboy

Kamen Rider Blade 33: Just appreciating the sheer number of different varieties of shitty 00's cheap digital TV cameras, all with different recording quality, that went into this sequence of Trial D hopping on top of Kotaro's range rover. XD

#toksatsu #KamenRider #KamenRiderBlade

Fedi Software of the week: JustMyToots :MastodonDE:!

JustMyToots does a singular simple thing: display just your toots! No reposts, only your posts. So, for example:

justmytoots.com/@ErikUden@mast

Displays only my posts, not all the things I repost! You don't even need to sign up or make an account, all you have to do is enter your Fediverse Tag (e.g. “@​ErikUden​@mastodon.de”) behind the backslash of the URL! That's it! Have fun Fedizens :fediverse:

If you wanna be notified when Kitsune Tails (think gay furry weeb mario) comes out, boost this post! I'll edit it when the game releases, and you should receive a notification!

More info/Steam wishlist: kitsunegames.com/kitsunetails

A week ago, a driver turning right at 4th/King killed for a four year old. Today at the vigil organized by WalkSF and other non-profits, SFMTA said it would take 3 weeks to do a “quick build” to make the intersection safer. That's too long to wait. So we did our own quick build tonight and closed one of the turn lanes

Jupes just bounced into my office

Jupes: <waving hands, overjoyed> I just MADE A PHONE CALL! BY MYSELF!

Me: You DID? YOU? My shy little autistic hobbit baby?

Jupes: YES! And I wrote a script! It helped so much! I sounded like a real human being!

Me: I’m so proud of you! GOOD JOB! That’s wonderful! Also you’re adorable, can I share this?

Jupes: Yes! But if you have neurodivergent people who read your posts, be sure to mention the SCRIPT! Scripts are the BEST! It helped me so much!

@eon oooh, that MeiLong Kilominx is pretty. I love the star shape in the center of each face

Yesterday, the best news which has ever come out during my lifetime, did. There's going to finally be an HIV cure. It's a ways down the road, but this all but guarantees it.

medicalxpress.com/news/2023-08

Here's the original paper explaining what was done in detail. Again, it's going to be a few more years before this is on the shelf, but there's finally hope for the end of HIV.

nature.com/articles/s41434-023

Here's one of the two papers where the technology germinated about a decade ago. Note that the last paper was SIV instead of HIV, but it's such a good model, it almost always translates to humans.

nature.com/articles/nbt.2647

Here's the other one. If you don't like reading original source materials like this, or want to read the first announcement with the details on the good news, I'll sum up...

nature.com/articles/nbt.2623

This is a gene therapy which inactivates HIV/SIV by entering the virus itself and editing the genome. This is cool in and of itself, but it is meaningful because it does a thing called "draining the viral reservoir". This is what makes it a cure and not just a treatment.

The reason why you can only suppress, and not eradicate viruses, is because they will go into a dormant state and hang out for years and then re-deploy, and you're back where you started.

This is why, as amazing as antivirals are, you're generally stuck taking them forever.

This is also why Sovaldi is such a big deal: it actually *cures* Hepatitis C, which previously was only treatable. You take it (along with other things) for twelve weeks, and at the end you are free of the virus. This is a first. No other cures for viruses exist.

And now there's a method to drain the viral reservoir and inactivate HIV. And this isn't just the best news of my lifetime, but it also paves the way for therapies to cure Hep B, and any number of others.

I am so excited, so happy, so hopeful.

✨💖✨

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Computer Fairies is a Mastodon instance that aims to be as queer, friendly and furry as possible. We welcome all kinds of computer fairies!