a tiny fairy @atinyfairy@computerfairi.es

Taking walks at the lake with the Gameboy Camera is becoming a more regular thing.

It's nice to have something small but not innately serious, like my Fuji GFX, to carry around, and the results are super fun!

I haven't been feeling up to hiking for mushroom photos lately though, and I really would like to get back out before fall hits!
.
#lazyhobbies #photography #digitalart #pixelart #birding #birdphotography #gameboy

Kamen Rider Blade 33: Just appreciating the sheer number of different varieties of shitty 00's cheap digital TV cameras, all with different recording quality, that went into this sequence of Trial D hopping on top of Kotaro's range rover. XD

#toksatsu #KamenRider #KamenRiderBlade

Fedi Software of the week: JustMyToots !

JustMyToots does a singular simple thing: display just your toots! No reposts, only your posts. So, for example:

https://justmytoots.com/@ErikUden@mastodon.de

Displays only my posts, not all the things I repost! You don't even need to sign up or make an account, all you have to do is enter your Fediverse Tag (e.g. “@​ErikUden​@mastodon.de”) behind the backslash of the URL! That's it! Have fun Fedizens

If you wanna be notified when Kitsune Tails (think gay furry weeb mario) comes out, boost this post! I'll edit it when the game releases, and you should receive a notification!

More info/Steam wishlist: https://kitsunegames.com/kitsunetails

The effects of air pollution on peoples' health are so stark that it only took one week after the closure of a coal coking plant in Pittsburgh for nearby cardiovascular ER visits to drop by 42%. #climate #climatechange #ClimateCrisis https://insideclimatenews.org/news/13082023/when-a-steel-plant-closed-in-pittsburgh-cardiovascular-er-visits-plunged/?utm_source=InsideClimate+News&utm_campaign=e3c5e4789c-EMAIL_CAMPAIGN_2023_08_19_01_00&utm_medium=email&utm_term=0_29c928ffb5-e3c5e4789c-329642993

A week ago, a driver turning right at 4th/King killed for a four year old. Today at the vigil organized by WalkSF and other non-profits, SFMTA said it would take 3 weeks to do a “quick build” to make the intersection safer. That's too long to wait. So we did our own quick build tonight and closed one of the turn lanes

Jupes just bounced into my office

Jupes: <waving hands, overjoyed> I just MADE A PHONE CALL! BY MYSELF!

Me: You DID? YOU? My shy little autistic hobbit baby?

Jupes: YES! And I wrote a script! It helped so much! I sounded like a real human being!

Me: I’m so proud of you! GOOD JOB! That’s wonderful! Also you’re adorable, can I share this?

Jupes: Yes! But if you have neurodivergent people who read your posts, be sure to mention the SCRIPT! Scripts are the BEST! It helped me so much!

If Castlevania would've never left NES 🦇 #aseprite #pixelart #nes

Yesterday, the best news which has ever come out during my lifetime, did. There's going to finally be an HIV cure. It's a ways down the road, but this all but guarantees it.

https://medicalxpress.com/news/2023-08-treatment-based-gene-safely-effectively.html

Here's the original paper explaining what was done in detail. Again, it's going to be a few more years before this is on the shelf, but there's finally hope for the end of HIV.

https://www.nature.com/articles/s41434-023-00410-4

Here's one of the two papers where the technology germinated about a decade ago. Note that the last paper was SIV instead of HIV, but it's such a good model, it almost always translates to humans.

https://www.nature.com/articles/nbt.2647

Here's the other one. If you don't like reading original source materials like this, or want to read the first announcement with the details on the good news, I'll sum up...

https://www.nature.com/articles/nbt.2623

This is a gene therapy which inactivates HIV/SIV by entering the virus itself and editing the genome. This is cool in and of itself, but it is meaningful because it does a thing called "draining the viral reservoir". This is what makes it a cure and not just a treatment.

The reason why you can only suppress, and not eradicate viruses, is because they will go into a dormant state and hang out for years and then re-deploy, and you're back where you started.

This is why, as amazing as antivirals are, you're generally stuck taking them forever.

This is also why Sovaldi is such a big deal: it actually *cures* Hepatitis C, which previously was only treatable. You take it (along with other things) for twelve weeks, and at the end you are free of the virus. This is a first. No other cures for viruses exist.

And now there's a method to drain the viral reservoir and inactivate HIV. And this isn't just the best news of my lifetime, but it also paves the way for therapies to cure Hep B, and any number of others.

I am so excited, so happy, so hopeful.

✨💖✨

found the other one

Loading bars explained:

Real talk, your precious 3d Zeldas are Zelda 2's spiritual successor and that's why Ocarina of Time had dark link, ironknuckles, lizalfos, volvagia (aka danger noodle), sages named after its towns, dungeons called temples, and complex sword combat.

"Nintendo pretends z2 doesn't exist" my ass. The whole series is modeled in its image now, it was just ahead of its time.

I adore this comic by by @elisegravel.

“So, yeah, YOU can be a scientist, too!” #science #art #education

I threatened I was gonna do this, YOU effed around and now it's time to find out, so here it is, a full short comic starring Trans Kid Ally Roxanne Wolf and Little Kid Nikki. Witness her in all her radical supportive glory!

https://t.me/ribnoseart/142

#RoxanneWolf #fnaf #fnafsb #myart #transally #animatronic

A protein that disrupts cells’ energy centers may be a culprit in chronic fatigue syndrome

"New study offers clues as to how exhaustion could arise in people with ME/CFS—and potentially related conditions such as Long Covid"

14 AUG 20233

https://www.science.org/content/article/protein-disrupts-cells-energy-centers-may-be-culprit-chronic-fatigue-syndrome

#MedMastodon
#LongCovid
#ME/CFS

New Blog Post: Executive Function Theft

http://hedgehoglibrarian.com/2023/08/14/executive-function-theft/

In which I seek to name something I keep encountering...

Here is a statement from a West Virginia Linguistics professor whose entire department has been eliminated. It provides additional context to the Provost's decision to cancel 38 majors and the tenure and untenured faculty lines associated with them.

#highered #education #tenure #WVU #academicfreedom #academic #law #lawfedi #lawprofs

https://community.wvu.edu/~jokatz/Closure/?fbclid=IwAR1BIcLhe__wEivDYWWz2UeyUHvFuiGg3T2KDtHdlS93X-_KPi2gM-YFbbI_aem_ATi1jeijVosmXwGlwcoYwc8OU1e8tXm08Y0nPDH2hdMqqHYZKNN3R8Qmr3nLw1tXKrM&mibextid=Zxz2cZ

This is why they are so poor at absorption compared to the claims and why doctors struggle with what constitutes heavy bleeding. The research was published LAST MONDAY. A week ago today.