I got a Compaq Deskpro ENS/P600 (the EN SFF [for "Slim Form Factor"] series) without a hard drive and neglected in a very dusty business environment.
I gambled on a small SSD and a SATA to desktop IDE adapter, cleaned everything inside and out, and installed the SSD. The Windows 98SE install CD recognized it.
I had to spend an entire evening locating the relevant Softpaq files (only four out of a few dozen thousand with cryptic names).
The insides, although pretty much entirely proprietary, is surprisingly accessible. The only things needing a screwdriver to remove are the expansion cards.
The most annoying proprietary problem is the CD/DVD cable: I'm pretty sure it has the right number of pins for an IDE cable, but both ends are smaller and the pins thinner and more closely spaced than standard IDE connectors.
Also, the DVD-ROM drive is the only thing with a date code I could find: It was made in 2000.