I occasionally forget the plot of that one book on my Mount To Be Read, and look it up on Goodreads to decide if I want to read it next. And I'm always surprised/amused/annoyed to see this one question/answer pair below it.

It's
Q: "Is the main character, Denise, Queer?"
A: "No. Denise is autistic. Her sister, Iris, is transgender (i.e., used to be her brother)."