@whitequark Indeed. The extent to which arsenic can substitute for phosphorus in biochemistry was a matter of some dispute many years ago, when a questionable paper appeared claiming the discovery of organisms that could actually _use_ arsenic in the same manner as phosphorus.
@whitequark I do not think it was. The authors continue to defend the work, anyway--at least as I recall.
@mona Oh I remember that paper. Did it get retracted in the end?