Alyx Woodward (obsolete) @Alyx@computerfairi.es

blech. had second thoughts about continuing this impromptu toot series of mine, but shit, I'm a chemist. if I tossed away everything of value just because it came from problematical sources, I'd have to throw my whole library away

anyway, page 5 of "Parallax".

https://www.parallaxcomic.com/comic/page-05

looks like Chara has a name of their own, "Lomax Torchstone". what sort of name is THAT? I kinda _preferred_ "Chara"

oh, well, "Lomax" it is

🔴 booooo

I thought you said that wasn't you!

well, that's neat I guess. can't imagine ever carrying this one out

looks like some _internal_ alkynes were used, yielding 2,3-disubstituted indoles with good regioselectivity (i.e. even though two possible indoles could be obtained, generally only one was obtained in quantity). it's not clear to me from the provided examples what controls the regioselectivity

slightly elaborate method, although conceptually it's simple enough: the precursors for the indole are N-acetylphenylhydroxyamine and a terminal alkyne, 1-hexyne, yielding N-acetyl-2-n-butylindole. the hitch is what's used for catalysis: zinc trifluoromethanesulfonate, the silver salt of N,N-bis(trifluoromethanesulfonyl)imine (a strong acid that supplies a _highly_ non-nucleophilic anion), and a complex of gold(I) with a very bulky triarylphosphite ligand, that needs to be made from scratch

bleh, slipped into inactivity again. I blame Chara

🔴 we've been busy!

I know, I know, I'm kidding! anyway, let's do an _Organic Syntheses_ roulette again

the word is "compare"

oh haha I recognize the _first_ hit already, it came up once (think I might have posted that one to Twitter not here, it was a synthesis of an iridium(III) complex of 2-phenylpyridine

so here's the second hit

http://orgsyn.org/demo.aspx?prep=v95p0015

synthesis of a 2-substitute indole

@chara_dreemurr@plural.cafe you are not the Kwisatz Haderach

@chara_dreemurr@plural.cafe watch The Omen then hehe

@NovaSquirrel sticks in my craw how often the difference between a $500 appliance and a $1500 appliance is, like, ten cents of electronics. hey look! you can see both the time and the temperature on separate displays!!! it's MAGIC

@NovaSquirrel I think having both the temp and the time be on the same display is just shitty UX. displays are cheap

@fribbledom transportation should simply be a property of a city. simple as that

the idea that people in a city should have to see to their own transportation is...unhinged

"oh but choice" oh give me a break. there's ways of managing that anyway. most people just wanna get from A to B, we're not looking to own a substitute for a personality in the form of a car

https://youtu.be/uR_2MMar0s0

@chara_dreemurr@plural.cafe maybe nothing's going on at all and you're just accidentally having a lot of traumas triggered in a flurry and it seems like you're under external pressure when you're not.

I'm actually semi-inclined to take Mono's offer. like, if he wants to come back to join in this fun, then let 'em; at least he'll be comic relief in his vests and ties and those silly panama hats

and who knows, maybe we could use a detective.

@chara_dreemurr@plural.cafe well...I won't go that far, but I'll tell you this much

I think we can be pretty certain there are a bunch of people here, nestled in deep on a couple instances, who really and truly despise you and haven't ever stopped because they're just frozen. have you seen any sign that any of these people who deadname you and scream abuse at you every time you brush against 'em wrong...you see any evidence these people EVER grow up?

@chara_dreemurr@plural.cafe haha! so that's got Athene on your mind? feel like the Furies are after you?

@chara_dreemurr@plural.cafe on Twitter resentments get knocked out of people (ot they just go fash or something.) here, one senses they linger

this is a place people DON'T deal with their shit. nothing here to make 'em

maybe you should take the others away from here. keep a token presence. maybe report in from Tumblr or wherever. demon Chara ain't going anywhere

also we should figure out where non plush Kel went

@chara_dreemurr@plural.cafe yeah

honestly

think Kara might have been right about this place

feels more and more unsafe in a bad way. Twitter is unsafe in a way we've learned to route around.

don't trust it here. none of have for a while

@chara_dreemurr@plural.cafe and I think you could just use the domain name directly, have it direct to Tumblr

@chara_dreemurr@plural.cafe also gonna make a paradoxical case for heading for Tumblr. seems like the worst idea ever but I have a hunch you will be able to hide among the noise better there

just Iike you hold your own best on Twitter

and you will meet your people, Chara *laughs* x=D

@chara_dreemurr@plural.cafe you remember old Mono, like, the tweedy unicorn with a monocle who went off to the farm to be St. Mono and eats grass with a knife and fork and all that

remember how he loved Kamen Rider W