Alyx Woodward (obsolete) @Alyx@computerfairi.es

@avi reminds me of this song

https://youtu.be/Nxls60aYSZA

@DarkWitchClaire awwww :=)

@DarkWitchClaire *pets the girl* :=3

wait a sec @chara_dreemurr@plural.cafe what about all that stuff about Ralsei

@Shadejackrabbit
tired: Nazis making fediverse instances
wired: Nazis basically running Twitter

(like, we still use it, Chara and me, but we've got no illusions about the place. it's like a big city where the cops are all on the take)

@azushark sweeeeet

@chara_dreemurr@plural.cafe *balls a fist* you know, Mona once said she'd hurt you if you hurt Kara, and...well, you can't lie and say you didn't, so maybe I'll make good on the promise

*relaxes* not today though. I guess it was all worth it

(damn though, Chara, you took some massive chances with her)

@chara_dreemurr@plural.cafe you are such a nerd

@SoniEx2@sleeping.town always! :=)

still pissed at you. you were cruel to us

but I like to think you helped too

glad you're feeling better.

anyway, that's one to file away for later consideration I think!

but "nitroxyl" radicals with the >N-O˙ group can be remarkably stable, especially here where there's bulky groups immediately adjacent. TEMPO and substituted derivatives like 4-acetamido-TEMPO (used in this _Organic Synthesis_ procedure) have been found to be versatile reagents for organic oxidations

in use, the nitroxyl group is oxidized by some auxiliary oxidant (the Oxone, here) to an N-oxammonium group, >N⁺=O, which is the active oxidizing species

"TEMPO" is a common abbreviation for 2,2,6,6-tetramethylpiperidinyl-N-oxyl, a rare example of a _stable free radical_. put a pic of it down below

most chemical compounds have all their electrons in pairs. each atomic or molecular orbital can hold two, of opposing spin. molecules with only _one_ electron in an orbital are *generally* unstable under usual conditions, highly reactive and short-lived species that like to grab or give up an electron from anything they bash into

they're making lauronitrile, the 12-carbon straight-chain nitrile derivative of lauric acid (dodecanoic acid), from laurylamine

the oxidant is "Oxone", a trade name for potassium peroxymonosulfate. (it's a pool chemical, I happen to know, a non-chlorine pool disinfectant). catalysts, "acetamido-TEMPO" with pyridinium bromide in pyridine and methylene chloride, carried out under nitrogen

so, what's this "TEMPO" stuff?

and I'll do an _Organic Syntheses_ random-word roulette

random word of the day is..."tire"

http://orgsyn.org/demo.aspx?prep=v95p0060

ooh, this one's rather curious. an unusual reaction: oxidation of a primary amide to a _nitrile_, so... R-CH2NH2 to R-C≡N. I can see that being handy, a way to get at nitriles without having to deal with cyanide (the usual method for nitrile synthesis is nucleophilic substitution of alkyl halides etc. with cyanide. tasty stuff, it's not)

well, today ended up pretty well, so I can do another page of Parallax!

https://www.parallaxcomic.com/comic/page-04

yeah, Chara's in a school

🔴 THAT IS NOT ME

that's totally you, Chara. anyway, kinda hard to tell anything else. for some reason a physics class is starting at five minutes after noon. oh, eh, actually I guess Chara is late--

🔴 that wouldn't be me. if I was five minutes late to a class I just wouldn't go at all. I told you it wasn't me

despite everything it's still you

@chara_dreemurr@plural.cafe that red-blue-green thing you're doing had better not be some kinda color charge reference or I'm asking the Monad for my money back