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doom 

@kiilas I like old Doom more too. don't like the ginormous sprawling levels of Doom II

@Canageek@cybre.space @kara_dreamer@plural.cafe but that's just the point isn't it? people love The Team(tm) but that's fake. it's loving something that's not real. the fans despise the actual players and basically think they should be doing what they do for free

making a fart joke (because I've forgotten way too much chemistry over the years) 

@USBloveDog never, I'm guessing. I prefer the term "isonitrile" myself ;=3

the reactions are pretty straightforward. aminoacetaldehyde diethyl acetal (or, 2,2-diethoxyethylamine, if you like) is turned into the formamide with propyl formate (why propyl formate? the reaction is carried out at reflux, suppose propyl formate boils at a high enough temperature to make the reaction work)

then the formamide is dehydrated to the isocyanide with the reagent you get from reacting carbon tetrachloride and triphenylphosphine. that's a trick a few uses (see the "Appel reaction")

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okay, one more for the road

did the random word thing, and here's the first hit in _Organic Synthesis_ with the word "overflow". ("untidy" gave nothing at all)

synthesis of 2,2-diethoxyethyl isocyanide! well, that's a thing I guess. it probably stinks to high heaven (organic isocyanides are famously stinky)

ah yeah they even warn you:

Caution: All the operations must be conducted in an efficient hood because the isocyanide has an obnoxious odor.

orgsyn.org/demo.aspx?prep=v82p

Twitter, maybe leaving 

well I got my own Twitter now (first tweet twitter.com/AlyxWoodward/statu) so I guess I'll be on my bullshit there

bleh

I don't quite wanna ditch this account (seeing as how I've barely given it a chance) but I don't think I fit in here and nobody has taken notice of the kind of physical science nerd shit I wanna talk about

it sucks and I'm not happy but whaddya do

just try again somewhere else, like always

@Nine :=3 I'm not a sheep but, you know, fellow hooved creature. I wouldn't mind be a (female) ram!

fascist culture wars 

i will not let fash take the spelling "fren". goddamnit. i feel like every day these fuckers lick something and declare "this is mine now." don't let them have it! symbolism matters and their feeble attempts to taint symbols like bread, clowns, and an adorably misspelling of "friend" can be overcome. together, we are strong! ✊

ukpol 

some people really love it when you ease up the pressure on their neck just a little. so much so that they don't for one moment imagine a world where the boot is gone entirely

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fascists PSA 

@Zero_Democracy@snouts.online do these fuckers have to corrupt literally everything (yeah they do don't they, it's a freakin' compulsion)

@Alyx "why does this cider taste like fish?"

"hey, I didn't know exactly which genes to copy over, I just copied a load of them"

"ah, the stack overflow approach to gene editing"

Reason #7812 I'm not allowed in genetics labs: glowy trees

I want like, bio luminescent apple trees

Plant them along paths

Save a load on street lighting

Also make glowy cider from them

gonna be moving back to Twitter. feel like maybe I'll get more interest for the kinda science / engineering stuff that I wanna spout off, here

@noiob people are laughing at this (with good reason) but I think it's kinda clever they figured out some way you could send a bit stream to a light bulb

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Computer Fairies is a Mastodon instance that aims to be as queer, friendly and furry as possible. We welcome all kinds of computer fairies!